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Image Search Results
Journal: PLoS ONE
Article Title: A Contributing Role for Anti-Neuraminidase Antibodies on Immunity to Pandemic H1N1 2009 Influenza A Virus
doi: 10.1371/journal.pone.0026335
Figure Lengend Snippet: The GenBank sequences of the NA of Solomon, Brisbane, Tennessee and California were aligned using the clustalW alignment program (BioEdit software, Windows 95/98/NT). Numbers to the left of each line indicates amino acid position. Gaps in the alignment are represented as dashed lines. A) Sequences that are shaded in grey indicate identical amino acids between the full length NA of H1N1 viruses. The black arrow indicates the starting sequences of the ectodomain for each virus strain (residue 82 to end).* assumption that the NA sequence of Solomon has identical residues at C-terminus. B) The percent identity of the NA ectodomain between Solomon, Brisbane, Tennessee viruses compared to California was calculated using BioEdit.
Article Snippet: To determine the percent homology between each seasonal and pandemic ectodomain sequences, a
Techniques: Software, Virus, Residue, Sequencing
Journal: PLoS Pathogens
Article Title: Serotonin Signaling in Schistosoma mansoni : A Serotonin–Activated G Protein-Coupled Receptor Controls Parasite Movement
doi: 10.1371/journal.ppat.1003878
Figure Lengend Snippet: The amino acid sequences of known and predicted serotonin receptors were aligned using the ClustalW method and a Neighbor-Joining Best Tree was constructed from the alignment. The alignment included representative examples of all major classes of serotonergic GPCRs but only three clades are shown for simplicity. These include type 2 serotonin receptors (5HT2), type 7 (5HT7) and structurally related type 1 and type 5 receptors (5HT1/5). The outgroup in the alignment (not shown) was a distantly related rat metabotropic glutamate receptor (NP_058707). The tree was rooted to the outgroup and was tested by bootstrap analysis with 1000 iterations. The length of the branches is proportional to the genetic distance between sequences. Sequences were all obtained from the National Center for Biotechnology Information (NCBI). S. mansoni sequences are designated by their S. mansoni GeneDB “smp”designation number and are marked by arrows. Accession numbers for the remaining sequences are as follows: 5HT2_Drosophila (NP_730859); 5HT2_Lymnae (AAC16969.1), 5HT2(ser-1)_C. elegans (AAC15778); 5HT2B_Xenopus (NP_001082744); 5HT2A_human (NP_000612); 5HT2A_mouse (NP_766400); 5HT2B_human (NP_000858); 5HT2C_human (NP_000859); 5HT5B_mouse (NP_034613.2); 5HT5A_human (NP_076917.1); 5HT1_Helisoma (AAQ95277.1); 5HT1A_Xenopus (NP_001079299.1); 5HT1A_human (NP_000515.2); 5HT1A_chicken (NP_001163999.1); 5HT1D_dog (P11614); 5HT1A_pufferfish (O42385); 5HT1_Aplysia (NP_001191550); 5HT1(ser-4)_C. elegans (NP_497452); 5HT_Haemonchus (AAO45883); 5HT7_Xenopus (NP_001079253.1); 5HT7_human (NP_062873.1); 5HT7_chicken (NP_001167605.1) 5HT7_Helisoma (AAQ84306.1); 5HT7_Meleagris (XP_003206102); 5HT7_zebrafish (XP_690599); 5HT7_Clonorchis (GAA29051); 5HT7_Aedes (AF296125); 5HT7 (ser-7)_C. elegans (NP_741730); 5HT_Dugesia.1 (BAA22404); 5HT_Dugesia.4 (BAA22403); 5HT7_Dugesia (BAI44327.1); 5HT4_chicken (XP_414481.2); 5HT4_human (NP_000861.1); 5HT6_chicken (NP_001166911.1); 5HT6_human (NP_000862.1); 5HT6_mouse (NP_067333.1); ratmGlu.8393487; mGluR1_rat (NP_058707).
Article Snippet:
Techniques: Construct